Pyrenebutyrate Pt(IV) Complexes with Nanomolar Anticancer Activity

• Principais autores: Anife Ahmedova (Autor), Rositsa Mihaylova (Autor), Silviya Stoykova (Autor), Veronika Mihaylova (Autor), Nikola Burdzhiev (Autor), Viktoria Elincheva (Autor), Georgi Momekov (Autor), Denitsa Momekova (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Research on platinum-based anticancer drugs continuously strives to develop new non-classical platinum complexes. Pt(IV) prodrugs are the most promising, and their activation-by-reduction mechanism of action is being explored as a prospect for higher selectivity and efficiency. Herein, we present th...