Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs.

• Main Authors: Leonardo M Leony (Author), Natália E M Freitas (Author), Rodrigo P Del-Rei (Author), Claudia M Carneiro (Author), Alexandre B Reis (Author), Ana Maria Jansen (Author), Samanta C C Xavier (Author), Yara M Gomes (Author), Edmilson D Silva (Author), Mitermayer G Reis (Author), Deborah B M Fraga (Author), Paola A F Celedon (Author), Nilson I T Zanchin (Author), Filipe Dantas-Torres (Author), Fred L N Santos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Dogs are considered sentinels in areas of Trypanosoma cruzi transmission risk to humans. ELISA is generally the method of choice for diagnosing T. cruzi exposure in dogs, but its performance substantially depends on the antigenic matrix employed. In previous studies, o...