Vulnerabilities of the SARS-CoV-2 Virus to Proteotoxicity-Opportunity for Repurposed Chemotherapy of COVID-19 Infection

• Main Authors: Maryam S. Al-Motawa (Author), Hafsa Abbas (Author), Patrick Wijten (Author), Alberto de la Fuente (Author), Mingzhan Xue (Author), Naila Rabbani (Author), Paul J. Thornalley (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The global pandemic of COVID-19 disease caused by infection with the SARS-CoV-2 coronavirus, has produced an urgent requirement and search for improved treatments while effective vaccines are developed. A strategy for improved drug therapy is to increase levels of endogenous reactive metabolites for...