Lipidomics of cyclophosphamide 4‐hydroxylation in patients receiving post‐transplant cyclophosphamide

• Main Authors: Sandi L. Navarro (Author), Zihan Zheng (Author), Timothy W. Randolph (Author), Ryotaro Nakamura (Author), Brenda M. Sandmaier (Author), David Hockenbery (Author), Jeannine S. McCune (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Biomarker‐guided dosing may improve the efficacy and toxicity of cyclophosphamide (CY); however, clinical studies evaluating their association with the area under the plasma concentration-time curve (AUC) of CY and its metabolites are time‐ and resource‐intensive. Therefore, we sought to id...