Predicting the Effects of Carbapenem/Carbapenemase Inhibitor Combinations against KPC-Producing <i>Klebsiella pneumoniae</i> in Time-Kill Experiments: Alternative versus Traditional Approaches to MIC Determination
Traditionally, the antibacterial activity of β-lactam antibiotics in the presence of β-lactamase inhibitors is determined at the fixed inhibitor concentration. This traditional approach does not consider the ratio of antibiotic-to-inhibitor concentrations achieved in humans. To explore whether an al...
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| Main Authors: | , , , , , |
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| Format: | Book |
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MDPI AG,
2021-12-01T00:00:00Z.
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