Time since onset of disease and individual clinical markers associate with transcriptional changes in uncomplicated dengue.

• Main Authors: Cornelia A M van de Weg (Author), Henk-Jan van den Ham (Author), Maarten A Bijl (Author), Fatih Anfasa (Author), Fatiha Zaaraoui-Boutahar (Author), Beti E Dewi (Author), Leonard Nainggolan (Author), Wilfred F J van IJcken (Author), Albert D M E Osterhaus (Author), Byron E E Martina (Author), Eric C M van Gorp (Author), Arno C Andeweg (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Dengue virus (DENV) infection causes viral haemorrhagic fever that is characterized by extensive activation of the immune system. The aim of this study is to investigate the kinetics of the transcriptome signature changes during the course of disease and the association of genes in these...