Bone Marrow-Derived Cells as a Therapeutic Approach to Optic Nerve Diseases

• Main Authors: Louise A. Mesentier-Louro (Author), Camila Zaverucha- (Author), Paulo H. Rosado- (Author), Almir J. Silva-Junior (Author), Pedro M. Pimentel-Coelho (Author), Rosalia Mendez-Otero (Author), Marcelo F. Santiago (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Following optic nerve injury associated with acute or progressive diseases, retinal ganglion cells (RGCs) of adult mammals degenerate and undergo apoptosis. These diseases have limited therapeutic options, due to the low inherent capacity of RGCs to regenerate and due to the inhibitory milieu of the...