Indole-3-Carboxylic Acid Enhanced Anti-cancer Potency of Doxorubicin via Induction of Cellular Senescence in Colorectal Cells

Background: Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Doxorubicin (DOX) is a widely utilized chemotherapy drug, but its efficacy is limited due to dose-dependent toxicity. Here, we aim to explore the effect of indole-3-carboxylic acid on DOX-induced senescence of CRC. M...

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Glavni autori: Yao Zhou (Autor), Yi Tang (Autor), Qingping Luo (Autor), Yuhang Hu (Autor), Wei Peng (Autor)
Format: Knjiga
Izdano: Polskie Towarzystwo Farmaceutyczne, 2024-04-01T00:00:00Z.
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