Indole-3-Carboxylic Acid Enhanced Anti-cancer Potency of Doxorubicin via Induction of Cellular Senescence in Colorectal Cells

• Main Authors: Yao Zhou (Author), Yi Tang (Author), Qingping Luo (Author), Yuhang Hu (Author), Wei Peng (Author)
• 格式: 图书
• 出版: Polskie Towarzystwo Farmaceutyczne, 2024-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Doxorubicin (DOX) is a widely utilized chemotherapy drug, but its efficacy is limited due to dose-dependent toxicity. Here, we aim to explore the effect of indole-3-carboxylic acid on DOX-induced senescence of CRC. M...