Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.

• Main Authors: Cristiano Marcelo Espinola Carvalho (Author), Jaline Coutinho Silverio (Author), Andrea Alice da Silva (Author), Isabela Resende Pereira (Author), Janice Mery Chicarino Coelho (Author), Constança Carvalho Britto (Author), Otacílio Cruz Moreira (Author), Renato Sergio Marchevsky (Author), Sergio Salles Xavier (Author), Ricardo Tostes Gazzinelli (Author), Maria da Glória Bonecini-Almeida (Author), Joseli Lannes-Vieira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: The factors contributing to chronic Chagas' heart disease remain unknown. High nitric oxide (NO) levels have been shown to be associated with cardiomyopathy severity in patients. Further, NO produced via inducible nitric oxide synthase (iNOS/NOS2) is proposed to play a role in Trypa...