Novel Calcium Phosphate Cement with Metformin-Loaded Chitosan for Odontogenic Differentiation of Human Dental Pulp Cells

• Main Authors: Wei Qin (Author), Jia-Yao Chen (Author), Jia Guo (Author), Tao Ma (Author), Michael D. Weir (Author), Dong Guo (Author), Yan Shu (Author), Zheng-Mei Lin (Author), Abraham Schneider (Author), Hockin H. K. Xu (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin is an old and widely accepted first-line drug for treating type 2 diabetes. Our previous studies demonstrate that metformin can stimulate the osteo/odontogenic differentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells and human dental pulp cells (DPCs). Due to t...