Optimization of Rifapentine-Loaded Lipid Nanoparticles Using a Quality-by-Design Strategy

This work aims to optimize and assess the potential use of lipid nanoparticles, namely nanostructured lipid carriers (NLCs), as drug delivery systems of rifapentine (RPT) for the treatment of tuberculosis (TB). A Box−Behnken design was used to increase drug encapsulation efficiency (EE) and loading...

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Bibliographic Details
Main Authors: Joana Magalhães (Author), Luise L. Chaves (Author), Alexandre C. Vieira (Author), Susana G. Santos (Author), Marina Pinheiro (Author), Salette Reis (Author)
Format: Book
Published: MDPI AG, 2020-01-01T00:00:00Z.
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