Using thrombocytopenia modeling to investigate the mechanisms underlying platelet depletion induced by pan‐proteasome inhibitors

Abstract Pan‐proteasome inhibitors (pPIs) significantly improve outcomes in patients with multiple myeloma; however, their indiscriminate inhibition of multiple proteasome and immunoproteasome subunits causes diverse toxicities, including thrombocytopenia. We investigated the mechanisms underlying t...

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Bibliographic Details
Main Authors: Floriane Lignet (Author), Andreas D. Becker (Author), Claude Gimmi (Author), Felix Rohdich (Author), Samer El Bawab (Author)
Format: Book
Published: Wiley, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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