Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders

• 主要な著者: Shuji Mizumoto (著者), Tomoki Kosho (著者), Shuhei Yamada (著者), Kazuyuki Sugahara (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2017-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The indispensable roles of dermatan sulfate-proteoglycans (DS-PGs) have been demonstrated in various biological events including construction of the extracellular matrix and cell signaling through interactions with collagen and transforming growth factor-β, respectively. Defects in the core proteins...