Involvement of <i>hpap2</i> and <i>dgkA</i> Genes in Colistin Resistance Mediated by <i>mcr</i> Determinants

• Main Authors: Alejandro Gallardo (Author), María Ugarte-Ruiz (Author), Marta Hernández (Author), Pedro Miguela-Villoldo (Author), David Rodríguez-Lázaro (Author), Lucas Domínguez (Author), Alberto Quesada (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plasmid-mediated colistin resistance (<i>mcr</i>) determinants are challenging the efficacy of polymyxins against Gram-negative pathogens. Among 10 <i>mcr</i> genes described so far, the major determinants <i>mcr-1</i> and <i>mcr-3</i> are found closel...