Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway

• Autori principali: Xiaowei Sun (Autore), Zhenhui Chen (Autore), Lu Yu (Autore), Weisen Zeng (Autore), Boyuan Sun (Autore), Hongying Fan (Autore), Yang Bai (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background: The relationships among intestinal dysbiosis, bile acid (BA) metabolism disorders, and ulcerative colitis pathogenesis are now recognized. However, how specific strains regulate BA metabolism to alleviate colitis is still unclear. This study investigated the effects of Bacteroides dorei...