PD-L1 expression in muscle invasive urothelial carcinoma: Comparison of SP142 and SP263 assay

• Main Authors: Gurudutt Gupta (Author), Sunil Pasricha (Author), Meenakshi Kamboj (Author), Anila Sharma (Author), N S Nayana (Author), Garima Durga (Author), Anurag Sharma (Author), Sudhir Rawal (Author), Anurag Meh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: High-grade urothelial carcinoma has a different molecular pathway than superficial low grade urothelial carcinoma, and is characterized by genomic instability. The high tumor mutation burden leads to neoantigen formation, evoking an immune response. The immune response has been keenly...