The Pathogenic Role of Smooth Muscle Cell-Derived Wnt5a in a Murine Model of Lung Fibrosis

• Egile Nagusiak: André Carmo-Fernandes (Egilea), Michelle Puschkarow (Egilea), Karin Peters (Egilea), Stefanie Gnipp (Egilea), Marcus Peters (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a disease characterized by extensive fibrosis of the lung tissue. Wnt5a expression was observed to be upregulated in IPF and suggested to be involved in the progression of the disease. Interestingly, smooth muscle cells (SMC) are a major source of Wnt5a in IPF...