Bone-Targeting Endogenous Secretory Receptor for Advanced Glycation End Products Rescues Rheumatoid Arthritis

• Main Authors: Tatsuo Takahashi (Author), Sayaka Katsuta (Author), Yusuke Tamura (Author), Nozomi Nagase (Author), Keita Suzuki (Author), Masaaki Nomura (Author), Shunji Tomatsu (Author), Ken-ichi Miyamoto (Author), Shinjiro Kobayashi (Author)
• Format: Book
• Published: BMC, 2013-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Rheumatoid arthritis (RA) is a chronic inflammatory synovitis that leads to the destruction of bone and cartilage. The receptor for advanced glycation end products (RAGE) is a multiligand membrane-bound receptor for high-mobility group box-1 (HMGB1) associated with development of RA by indu...