Mechanism of action of disulfiram and research advances in anti-glomerular basement membrane type glomerulonephritis

• Главные авторы: Yan-yu Zhang (Автор), Xin Lyu (Автор), Xiao-guang Huang (Автор), Xiao-jun Ren (Автор), Xue Wang (Автор), Wei-min Yu (Автор)
• Формат: ‌
• Опубликовано: Editorial Department of Journal of Clinical Nephrology, 2024-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Disulfiram is widely applied for treating chronic alcoholism. In recent years, researchers have proposed specific anti-cancer mechanisms by disulfiram, such as arresting the activity of acetaldehyde dehydrogenase （ALDH） and boosting intracellular reactive oxygen species （ROS）（reactive oxygen species...