Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma

• Main Authors: Jizhou Tan (Author), Ting Liu (Author), Wenzhe Fan (Author), Jialiang Wei (Author), Bowen Zhu (Author), Yafang Liu (Author), Lingwei Liu (Author), Xiaokai Zhang (Author), Songling Chen (Author), Haibiao Lin (Author), Yuanqing Zhang (Author), Jiaping Li (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cryoablation (CRA) and microwave ablation (MWA) are two main local treatments for hepatocellular carcinoma (HCC). However, which one is more curative and suitable for combining with immunotherapy is still controversial. Herein, CRA induced higher tumoral PD-L1 expression and more T cells infiltratio...