Predictive modeling of concentration-dependent viscosity behavior of monoclonal antibody solutions using artificial neural networks
ABSTRACTSolutions of monoclonal antibodies (mAbs) can show increased viscosity at high concentration, which can be a disadvantage during protein purification, filling, and administration. The viscosity is determined by protein-protein-interactions, which are influenced by the antibody's sequenc...
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Taylor & Francis Group,
2023-12-01T00:00:00Z.
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