Synthesis, In Vitro and In Vivo Evaluation of the N-ethoxycarbonylmorpholine Ester of Diclofenac as a Prodrug

The N-ethoxycarbonylmorpholine moiety was evaluated as a novel prodrug moiety for carboxylic acid containing drugs represented by diclofenac (1). Compound 2, the N-ethoxycarbonylmorpholine ester of diclofenac was synthesized and evaluated as a potential prodrug. The stability of the synthesized prod...

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Váldodahkkit: Jamal A. Jilani (Dahkki), Nasir M. Idkaidek (Dahkki), Karem H. Alzoubi (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: MDPI AG, 2014-04-01T00:00:00Z.
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