Sm29, but not Sm22.6 retains its ability to induce a protective immune response in mice previously exposed to a Schistosoma mansoni infection.

• Main Authors: Clarice Carvalho Alves (Author), Neusa Araujo (Author), Viviane Cristina Fernandes dos Santos (Author), Flávia Bubula Couto (Author), Natan R G Assis (Author), Suellen B Morais (Author), Sérgio Costa Oliveira (Author), Cristina Toscano Fonseca (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Fag: article
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BACKGROUND:A vaccine against schistosomiasis would have a great impact in disease elimination. Sm29 and Sm22.6 are two parasite tegument proteins which represent promising antigens to compose a vaccine. These antigens have been associated with resistance to infection and reinfection in individuals l...