MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations

• Main Authors: Shota Tobori (Author), Haruka Hiyama (Author), Takahito Miyake (Author), Yuichi Yano (Author), Kazuki Nagayasu (Author), Hisashi Shirakawa (Author), Takayuki Nakagawa (Author), Yasuo Mori (Author), Shuji Kaneko (Author)
• Format: Book
• Published: Elsevier, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gentle touch such as stroking of the skin produces a pleasant feeling, which is detected by a rare subset of sensory neurons that express Mas-related G protein-coupled receptor B4 (MrgprB4) in mice. We examined small populations of MrgprB4-positive neurons in the trigeminal ganglion and the dorsal r...