Cold-Pressed <i>Nigella Sativa</i> Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice

• Main Authors: Hsin Hsueh Shen (Author), Stephen J. Peterson (Author), Lars Bellner (Author), Abu Choudhary (Author), Lior Levy (Author), Leah Gancz (Author), Ariel Sasson (Author), Joseph Trainer (Author), Rita Rezzani (Author), Abraham Resnick (Author), David E. Stec (Author), Nader G. Abraham (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Excessive lipid accumulation in white adipose tissue (WAT) results in adipocyte hypertrophy and chronic low-grade inflammation, which is the major cause of obesity-associated insulin resistance and consequent metabolic disease. The development of beige adipocytes in WAT (browning of WAT) increases e...