Reduced High-Dose Radiation-Induced Residual Genotoxic Damage by Induction of Radioadaptive Response and Prophylactic Mild Dietary Restriction in Mice

• Main Authors: Bing Wang (Author), Kaoru Tanaka (Author), Takanori Katsube (Author), Kouichi Maruyama (Author), Yasuharu Ninomiya (Author), Guillaume Varès (Author), Cuihua Liu (Author), Hirokazu Hirakawa (Author), Masahiro Murakami (Author), Zeenath Fardous (Author), Nahida Sultana (Author), Kazuko Fujita (Author), Akira Fujimori (Author), Tetsuo Nakajima (Author), Mitsuru Nenoi (Author)
• Format: Book
• Published: SAGE Publishing, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radioadaptive response (RAR) describes a phenomenon in a variety of in vitro and in vivo systems that a low-dose of priming ionizing radiation (IR) reduces detrimental effects of a subsequent challenge IR at higher doses. Among in vivo investigations, studies using the mouse RAR model (Yonezawa Effe...