Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes

Impaired angiogenesis and endothelial dysfunction in type 2 diabetes constitute dominant risk factors for non-healing wounds and most forms of cardiovascular disease. We propose that diabetes shifts the 'angiogenic balance' in favor of an excessive anti-angiogenic phenotype. Herein, we rep...

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Main Authors: Milad S. Bitar (Author), Fahd Al-Mulla (Author)
Format: Book
Published: The Company of Biologists, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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