Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes
Impaired angiogenesis and endothelial dysfunction in type 2 diabetes constitute dominant risk factors for non-healing wounds and most forms of cardiovascular disease. We propose that diabetes shifts the 'angiogenic balance' in favor of an excessive anti-angiogenic phenotype. Herein, we rep...
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The Company of Biologists,
2015-01-01T00:00:00Z.
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A1234.567 |
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