Targeting Akt/PKB in pediatric tumors: A review from preclinical to clinical trials

The serine/threonine kinase Akt is a major player in the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway, and its modulation impacts multiple cellular processes such as growth, proliferation, and survival. Several abnormalities in this pathway have been do...

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Main Authors: Bruno Toson (Author), Isadora S. Fortes (Author), Rafael Roesler (Author), Saulo F. Andrade (Author)
Format: Book
Published: Elsevier, 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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