Targeting Akt/PKB in pediatric tumors: A review from preclinical to clinical trials
The serine/threonine kinase Akt is a major player in the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway, and its modulation impacts multiple cellular processes such as growth, proliferation, and survival. Several abnormalities in this pathway have been do...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-09-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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