Envenomations by Bothrops and Crotalus snakes induce the release of mitochondrial alarmins.

• Main Authors: Irene Zornetta (Author), Paola Caccin (Author), Julián Fernandez (Author), Bruno Lomonte (Author), José María Gutierrez (Author), Cesare Montecucco (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Skeletal muscle necrosis is a common manifestation of viperid snakebite envenomations. Venoms from snakes of the genus Bothrops, such as that of B. asper, induce muscle tissue damage at the site of venom injection, provoking severe local pathology which often results in permanent sequelae. In contra...