Serum metabolic disturbances associated with acute-on-chronic liver failure in patients with underlying alcoholic liver diseases: An elaborative NMR-based metabolomics study

• Main Authors: Umesh Kumar (Author), Supriya Sharma (Author), Manjunath Durgappa (Author), Nikhil Gupta (Author), Ritu Raj (Author), Alok Kumar (Author), Prabhat N Sharma (Author), V P Krishna (Author), R Venkatesh Kumar (Author), Anupam Guleria (Author), Vivek A Saraswat (Author), Gaurav Pande (Author), Dinesh Kumar (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Acute-on-chronic liver failure (ACLF), which develops in patients with underlying alcoholic liver disease (ALD), is characterized by acute deterioration of liver function and organ failures are secondary to that. The clear understanding of metabolic pathways perturbed in ALD-ACLF patient...