Indoxyl Sulfate Impairs Endothelial Progenitor Cells and Might Contribute to Vascular Dysfunction in Patients with Chronic Kidney Disease

• Main Authors: Cheng-Jui Lin (Author), Chih-Jen Wu (Author), Pei-Chen Wu (Author), Chi-Feng Pan (Author), Tuan-Jen Wang (Author), Fang-Ju Sun (Author), Hsuan-Liang Liu (Author), Han-Hsiang Chen (Author), Hung-I Yeh (Author)
• Format: Book
• Published: Karger Publishers, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Indoxyl sulfate (IS) is a protein-bound uremic toxin that accumulates in patients with chronic kidney disease (CKD). We explored the effect of IS on human early endothelial progenitor cells (EPCs) and analyzed the correlation between serum IS levels and parameters of vascular functi...