AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism

• Главные авторы: Monika Rech (Автор), Annika R. Kuhn (Автор), Joost Lumens (Автор), Paolo Carai (Автор), Rick van Leeuwen (Автор), Wouter Verhesen (Автор), Robin Verjans (Автор), Julie Lecomte (Автор), Yilin Liu (Автор), Joost J.F.P. Luiken (Автор), Ronny Mohren (Автор), Berta Cillero-Pastor (Автор), Stephane Heymans (Автор), Kèvin Knoops (Автор), Marc van Bilsen (Автор), Blanche Schroen (Автор)
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• Опубликовано: Elsevier, 2019-03-01T00:00:00Z.
• Предметы: article
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MicroRNA-103/107 regulate systemic glucose metabolism and insulin sensitivity. For this reason, inhibitory strategies for these microRNAs are currently being tested in clinical trials. Given the high metabolic demands of the heart and the abundant cardiac expression of miR-103/107, we questioned whe...