Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa

• Главные авторы: María José De Jesús Valle (Автор), Aranzazu Zarzuelo Castañeda (Автор), Cristina Maderuelo (Автор), Alejandro Cencerrado Treviño (Автор), Jorge Loureiro (Автор), Paula Coutinho (Автор), Amparo Sánchez Navarro (Автор)
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• Опубликовано: MDPI AG, 2022-07-01T00:00:00Z.
• Предметы: article
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A pharmaceutical vehicle based on lyophilized liposomes is proposed for the buccal administration of drugs aimed at systemic delivery through the sublingual mucosa. Liposomes made of egg phosphatidylcholine and cholesterol (7/3 molar ratio) were prepared and lyophilized in the presence of different...