Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa

• Main Authors: María José De Jesús Valle (Author), Aranzazu Zarzuelo Castañeda (Author), Cristina Maderuelo (Author), Alejandro Cencerrado Treviño (Author), Jorge Loureiro (Author), Paula Coutinho (Author), Amparo Sánchez Navarro (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A pharmaceutical vehicle based on lyophilized liposomes is proposed for the buccal administration of drugs aimed at systemic delivery through the sublingual mucosa. Liposomes made of egg phosphatidylcholine and cholesterol (7/3 molar ratio) were prepared and lyophilized in the presence of different...