Discordant immunohistochemistry in an unusual MLH1 gene variant in a case of Lynch syndrome

• Glavni autori: Prerana Nagabhushana (Autor), Snigdha Kumari (Autor), Minakshi Rohilla (Autor), Radhika Srinivasan (Autor), Aashima Arora (Autor), Pulkit Rastogi (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2021-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Immunohistochemistry for mismatch repair proteins and microsatellite instability testing are recommended screening methods for Lynch syndrome. They have a good sensitivity and specificity, allowing for directed genetic testing and diagnosis. We report a case of Lynch syndrome with retained MMR prote...