Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway

Abstract Background Sarcopenia and osteoporosis are common diseases that predominantly affect older individuals. The interaction between muscle and skeleton exerts pivotal roles in bone remodeling. This study aimed to explore the function of myoblast-derived exosomal Prrx2 in osteogenic differentiat...

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Main Authors: Yunchao Li (Author), Xiaoxiao Wang (Author), Changyu Pan (Author), Hui Yuan (Author), Xinyi Li (Author), Zejun Chen (Author), Haoyu He (Author)
Format: Book
Published: BMC, 2023-04-01T00:00:00Z.
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