Mitochondrial Generated Redox Stress Differently Affects the Endoplasmic Reticulum of Circulating Lymphocytes and Monocytes in Treatment-Naïve Hodgkin's Lymphoma

• Main Authors: Cecilia Marini (Author), Vanessa Cossu (Author), Matteo Bauckneht (Author), Sonia Carta (Author), Francesco Lanfranchi (Author), Francesca D'Amico (Author), Silvia Ravera (Author), Anna Maria Orengo (Author), Chiara Ghiggi (Author), Filippo Ballerini (Author), Paolo Durando (Author), Sabrina Chiesa (Author), Alberto Miceli (Author), Maria Isabella Donegani (Author), Silvia Morbelli (Author), Silvia Bruno (Author), Gianmario Sambuceti (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The redox stress caused by Hodgkin's lymphoma (HL) also involves the peripheral blood mononucleated cells (PBMCs) even before chemotherapy. Here, we tested whether lymphocytes and monocytes show a different response to the increased mitochondrial generation of reactive oxygen specie...