Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic stem cell

• Main Authors: Jiaxing Li (Author), Xiao Wang (Author), Jiayu Ding (Author), Yasheng Zhu (Author), Wenjian Min (Author), Wenbing Kuang (Author), Kai Yuan (Author), Chengliang Sun (Author), Peng Yang (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hematopoietic stem cell (HSC) transplantation is the only curative therapy for many diseases. HSCs from umbilical cord blood (UCB) source have many advantages over from bone marrow. However, limited HSC dose in a single CB unit restrict its widespread use. Over the past two decades, ex vivo HSC expa...