Live-imaging rate-of-kill compound profiling for Chagas disease drug discovery with a new automated high-content assay.
Chagas disease, caused by the protozoan intracellular parasite Trypanosoma cruzi, is a highly neglected tropical disease, causing significant morbidity and mortality in central and south America. Current treatments are inadequate, and recent clinical trials of drugs inhibiting CYP51 have failed, exp...
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| Main Authors: | , , , |
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| Format: | Book |
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Public Library of Science (PLoS),
2021-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |