Glyoxalase 2: Towards a Broader View of the Second Player of the Glyoxalase System

• Main Authors: Andrea Scirè (Author), Laura Cianfruglia (Author), Cristina Minnelli (Author), Brenda Romaldi (Author), Emiliano Laudadio (Author), Roberta Galeazzi (Author), Cinzia Antognelli (Author), Tatiana Armeni (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glyoxalase 2 is a mitochondrial and cytoplasmic protein belonging to the metallo-β-lactamase family encoded by the hydroxyacylglutathione hydrolase (HAGH) gene. This enzyme is the second enzyme of the glyoxalase system that is responsible for detoxification of the α-ketothaldehyde methylglyoxal in c...