Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA

• मुख्य लेखकों: Nour El-Mais (लेखक), Isabelle Fakhoury (लेखक), Sandra Abdellatef (लेखक), Ralph Abi-Habib (लेखक), Mirvat El-Sibai (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2021-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amounts of amino acids, including arginine. L-arginine i...