Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA

Abstract Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amounts of amino acids, including arginine. L-arginine i...

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Main Authors: Nour El-Mais (Author), Isabelle Fakhoury (Author), Sandra Abdellatef (Author), Ralph Abi-Habib (Author), Mirvat El-Sibai (Author)
Format: Book
Published: BMC, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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