Field cage studies and progressive evaluation of genetically-engineered mosquitoes.

• Main Authors: Luca Facchinelli (Author), Laura Valerio (Author), Janine M Ramsey (Author), Fred Gould (Author), Rachael K Walsh (Author), Guillermo Bond (Author), Michael A Robert (Author), Alun L Lloyd (Author), Anthony A James (Author), Luke Alphey (Author), Thomas W Scott (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A genetically-engineered strain of the dengue mosquito vector Aedes aegypti, designated OX3604C, was evaluated in large outdoor cage trials for its potential to improve dengue prevention efforts by inducing population suppression. OX3604C is engineered with a repressible genetic construct that cause...