Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy

• Главные авторы: Miao Shen (Автор), Jie Lu (Автор), Weiqi Dai (Автор), Fan Wang (Автор), Ling Xu (Автор), Kan Chen (Автор), Lei He (Автор), Ping Cheng (Автор), Yan Zhang (Автор), Chengfen Wang (Автор), Dong Wu (Автор), Jing Yang (Автор), Rong Zhu (Автор), Huawei Zhang (Автор), Yinqun Zhou (Автор), Chuanyong Guo (Автор)
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• Опубликовано: Hindawi Limited, 2013-01-01T00:00:00Z.
• Предметы: article
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Background. Hepatic ischemia-reperfusion (I/R) injury is a pivotal clinical problem occurring in many clinical conditions such as transplantation, trauma, and hepatic failure after hemorrhagic shock. Apoptosis and autophagy have been shown to contribute to cell death in hepatic I/R injury. Ethyl pyr...