Tumor Necrosis Factor-α Mediates the Blood-Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells

• Asıl Yazarlar: Tsuyoshi Nishioku (Yazar), Junichi Matsumoto (Yazar), Shinya Dohgu (Yazar), Noriko Sumi (Yazar), Kenji Miyao (Yazar), Fuyuko Takata (Yazar), Hideki Shuto (Yazar), Atsushi Yamauchi (Yazar), Yasufumi Kataoka (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2010-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The present study was designed to elucidate the involvement of tumor necrosis factor-α (TNF-α) release from activated microglia in the induction of blood-brain barrier (BBB) dysfunction in an in vitro co-culture system with mouse brain capillary endothelial cells (MBEC4) and microglia. Lipopolysacch...