Attenuating Atherosclerosis through Inhibition of the NF-κB/NLRP3/IL-1β Pathway-Mediated Pyroptosis in Vascular Smooth Muscle Cells (VSMCs)

• Main Authors: Shihuan Li (Author), Qingjie Li (Author), Qiaofeng Zhou (Author), Suqin Li (Author), Siqi Wang (Author), Qing Yao (Author), Changhan Ouyang (Author), Chao Liu (Author), Mincai Li (Author)
• Format: Book
• Published: Hindawi-Wiley, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. We investigated the effects of resveratrol (Res) and MCC950 on the pyroptosis of vascular smooth muscle cells (VSMCs) and the potential pathway. Methods and Results. Compared with the control (Con) group, the atherosclerosis (AS) group showed calcified nodules, which suggested that the ca...