Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

• Main Authors: Hugo M. Oliveira (Author), Jaqueline Stall (Author), Karina M.P.A. Coelho (Author), Viviane C. Silva (Author), Paulo H. C. Franca (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Introduction In Brazil, 8,000 new cases of childhood cancer are estimated each year, whose causes are still little known, although some have genetically determined factors. Approximately 70% of human cancers have alterations in the TP53 gene, which encodes the protein responsible for inhibi...