Plant Extracts and Phytochemicals Targeting α-Synuclein Aggregation in Parkinson's Disease Models

• Main Authors: Hayate Javed (Author), Mohamed Fizur Nagoor Meeran (Author), Sheikh Azimullah (Author), Abdu Adem (Author), Bassem Sadek (Author), Shreesh Kumar Ojha (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

α-Synuclein (α-syn) is a presynaptic protein that regulates the release of neurotransmitters from synaptic vesicles in the brain. α-Syn aggregates, including Lewy bodies, are features of both sporadic and familial forms of Parkinson's disease (PD). These aggregates undergo several key stages of...