Andrographolide and Epigallocatechin Gallate (EGCG) Lower the Risk of Addiction Induced by Nicotine and Cigarette Smoke Extract (CSE) in Mice

• Main Authors: Samirah Samirah (Author), Kurnia Indrayanti (Author), Ahmad Dzulfikri Nurhan (Author), Vida Softyana (Author), Nadya Ratri Pradipta (Author), Chrismawan Ardianto (Author), Yulistiani Yulistiani (Author), Mahardian Rahmadi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Nicotine, a psychoactive compound from the tobacco plant, produces a reward effect that potentially causes addiction. It is postulated that nicotine addiction occurs through increased reactive oxygen species production in nucleus accumbens, which causes damage to the endogenous antioxida...