Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen.

• Main Authors: Martin Montes (Author), Cesar Sanchez (Author), Kristien Verdonck (Author), Jordan E Lake (Author), Elsa Gonzalez (Author), Giovanni Lopez (Author), Angelica Terashima (Author), Thomas Nolan (Author), Dorothy E Lewis (Author), Eduardo Gotuzzo (Author), A Clinton White (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human strongyloidiasis varies from a chronic but limited infection in normal hosts to hyperinfection in patients treated with corticosteroids or with HTLV-1 co-infection. Regulatory T cells dampen immune responses to infections. How human strongyloidiasis is controlled and how HTLV-1 infection affec...