Model‐Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes

This analysis reports a quantitative modeling and simulation approach for oral dapagliflozin, a primarily uridine diphosphate‐glucuronosyltransferase (UGT)-metabolized human sodium‐glucose cotransporter 2 selective inhibitor. A mechanistic dapagliflozin physiologically based pharmacokinetic (PBPK) m...

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Main Authors: Heeseung Jo (Author), Venkatesh Pilla Reddy (Author), Joanna Parkinson (Author), David W. Boulton (Author), Weifeng Tang (Author)
Format: Book
Published: Wiley, 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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