Model‐Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes
This analysis reports a quantitative modeling and simulation approach for oral dapagliflozin, a primarily uridine diphosphate‐glucuronosyltransferase (UGT)-metabolized human sodium‐glucose cotransporter 2 selective inhibitor. A mechanistic dapagliflozin physiologically based pharmacokinetic (PBPK) m...
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| Formaat: | Boek |
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Wiley,
2021-02-01T00:00:00Z.
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A1234.567 |
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| Kopie 1 | Beschikbaar |